ProBiS Server

Introduction

There are two ProBiS web pages out there: ProBiS at http://probis.cmm.ki.si maintained at the National Institute of Chemistry, Slovenia, and ProBiS-CHARMMing at https://probis.nih.gov situated at the National Institutes of Health, USA. Why is that? ProBiS-CHARMMing has additional functions only available from inside NIH: it enables energy minimization of predicted protein-ligand complexes and their interaction energy calculation.

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Most Recent Citation

Konc, J., Miller, B. T., Stular, T., Lesnik, S., Woodcock, H. L., Brooks, B. R., and Janezic, D. ProBiS-CHARMMing: Web Interface for Prediction and Optimization of Ligands in Protein Binding Sites. J. Chem. Inf. Model., 2015, 55, 2308-2314.

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PDB ID: File: Chain ID(s):

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Pairwise Align Two Proteins or Binding Sites (optional) Pairwise Align Two Proteins or Binding Sites (optional)

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Release Notes

Mar 14 2016: Added color legend for superimposed proteins
Feb 23 2016: It is now possible to download the predicted ligands as text file
Feb 1 2016: Fixed clustering of protein and nucleic ligands, consequently there are much more in the output